What is the maximum IV dose of prochlorperazine (Compazine)?

The maximum intravenous dose of prochlorperazine (Compazine) is 10 mg. This medication is an antipsychotic commonly used for the treatment of severe nausea and vomiting. When administered intravenously, the dosing must be cautious because higher doses can increase the risk of potential side effects, including sedation, extrapyramidal symptoms, and other adverse reactions.

The 10 mg maximum dose is supported by clinical guidelines, ensuring that patients receive effective symptom relief while minimizing risks associated with overdose or adverse effects. Understanding this dosing limit is crucial for healthcare providers to safely manage and administer medications during procedures requiring moderate sedation, where sedation depth is carefully controlled to avoid complications.