What is the recommended intravenous dose of Ketamine for moderate sedation?

The recommended intravenous dose of Ketamine for moderate sedation is specifically in the range of 0.25-1.0 mg/kg. This dosage is established based on the pharmacological properties of Ketamine, which is an NMDA receptor antagonist used for its sedative, analgesic, and anesthetic effects. The chosen dose range is effective in achieving the desired level of sedation while minimizing the risk of adverse effects.

Dosing Ketamine within this range allows for individual patient factors, such as weight, medical history, and required sedation depth, to be considered. Additionally, this range supports the continuous monitoring of the patient's response during the sedation process, ensuring that further titration to effect can be safely achieved if needed. Proper understanding and application of this dosage range are crucial in a clinical setting to ensure patient safety and the effectiveness of sedation.