Which adverse effect is specifically noted for neonates using Chloral Hydrate?

The correct response highlights hyperbilirubinemia as a significant adverse effect associated with neonates using Chloral Hydrate. In neonates, their liver function is still developing, which can impact the way medications are metabolized. Chloral Hydrate is known to potentially interfere with bilirubin metabolism, leading to elevated levels of bilirubin in the bloodstream. This condition, known as hyperbilirubinemia, can pose serious risks, including jaundice and, in severe cases, kernicterus—a form of brain damage caused by excessive bilirubin.

Understanding this adverse effect is crucial for healthcare providers when considering the use of Chloral Hydrate in pediatric populations, particularly in neonates, who are more susceptible to these issues due to their immature hepatic systems. Recognizing the potential for hyperbilirubinemia can guide the medical team in monitoring and managing patients effectively during sedation protocols.